Good research requires productive theories and guidelines

Guidelines for good database selection and use in pharmacoepidemiology research.

The use of healthcare databases in research provides advantages such as increased speed, lower costs and limitation of some biases. However, database research has its own challenges as studies must be performed within the limitations of resources, which often are the product of complex healthcare systems. The primary purpose of this document is to assist in the selection and use of data resourc...

Good decision making requires good communication.

The methods used for regulatory decisions must facilitate three kinds of communication: (i) with individual experts who must translate their knowledge into usable form; (ii) among the experts whose pooled knowledge informs those choices; and (iii) between regulators and those affected by their choices. Decision-making methods vary in their reliance on expert judgement and computational methods ...

I-20: Good Science and Good Ethics@ WhyWe Should Discourage Payment for Eggs inStem Cell Research?

Background: To evaluate current scientific and legal trends in provision of human eggs for stem cell research and to propose a policy which is both ethically and scientifically sound Materials and Methods: Literature survey of European and US policies on payment for egg donation in somatic cell nuclear transfer (SCNT) research; comparative analysis of potential for success in SCNT and induced p...

What makes good guidelines?

In the last two decades, a large number of national and international treatment guidelines have been developed, to assist practioners in making decisions based on available evidence. However, according to a survey of schizophrenia practice guidelines for example [1], the methodological quality of the most guidelines was at best moderate. Hence, national and international institutions attempted ...

Membrane Research in a Global Context Requires Collaboration, not Competition!